产品货号:
Z39453
中文名称:
SPI1抗体
英文名称:
Anti-SPI1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SPI1 Antibody |
指标别名 | 31kDa transforming protein;OF;PU.1;SFPI1;SPI 1;SPI A;SPI1;Transcription factor PU.1 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | SPI1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human PU.1/Spi1 Binds to the PU-box,a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer.This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells.Also binds RNA and may modulate pre-mRNA splicing. |
实际分子量 | 40KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Transcription factor PU.1 is a protein that in humans is encoded by the SPI1 gene.This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development.The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes,and regulates their expression in coordination with other transcription factors and cofactors.The protein can also regulate alternative splicing of target genes.Multiple transcript variants encoding different isoforms have been found for this gene. |
Uniprot ID | P17947 |
推荐稀释比 | Western blot (WB) 1:500~2000 |
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